Fermentation for Superoxide Dismutase Production

Enzymes for feed are a new green feed additive with significant application effects. It can significantly improve the efficiency of feed utilization, improve immunity, reduce organic emissions and reduce the use of pharmaceutical additives. Thus, it can save feed, protect the environment, and animal product safety. It is an effective way to solve the above problems at the feed level from the source of the farming industry.

The endogenous or exogenous stimulation of the farm animal organism can lead to abnormal metabolism of the organism and the production of a large number of highly reactive oxygen molecules in a short period. This exceeds the reduction capacity of the body's antioxidant system and causes oxidative damage, which can easily cause damage to the animal's intestinal tract. This significantly decreases production performance, immunity, litter rate, and other production-related indicators.

Superoxide dismutase (SOD) is an essential component of the antioxidant enzyme system in biological systems, which is widely distributed in microorganisms, plants, and animals. Lifeasible, through years of experience, can screen and obtain a variety of SOD enzyme genes from different environmental genes and express them.

High SOD producing strains

• We can obtain strains with high SOD production through conventional mutagenesis breeding and genetic engineering breeding, and improve SOD yield by optimizing culture media and conditions.
• Through a technical route based on the structural characteristics of enzyme molecules and combined with bioinformatics design, we have established an efficient amplification and isolation technique for enzyme gene resources for rapid screening and effective evaluation of resources.
• To address the key issues of enzymatic performance and production cost of SOD enzymes for industrial application, we can improve the production strains and construct strains that can tolerate high temperatures of 80℃ for efficient expression of SOD production.
• We have not only perfected the SOD expression fermentation process, and the technology level continues to improve, the enzyme activity of the fermentation solution now reaches 5000U/ml, the production cost is ten times lower than the current commercial SOD enzyme, and its application cost is cheaper.

Lifeasible has rich experience in strain selection, development of high yield strains, optimization of the fermentation process, and application of SOD in microbial fermentation for SOD production. The SOD produced by microbial fermentation can be used directly in animal feed without the traditional purification process, and can also be used directly in the production of functional microecological preparations, etc. We are looking forward to cooperating with you to promote the gradual industrialization of microbial production of SOD. Please contact us for more information.