Astaxanthin Production by Fermentation

Astaxanthin, a carotenoid, is a highly promising nutritional pigment and antioxidant. Physiological studies have shown that astaxanthin has strong antioxidant and free radical scavenging properties. It can scavenge free radicals in the body produced by ultraviolet radiation and regulate the reduction of these damages caused by photochemistry. This improves pigmentation of aquatic and livestock skin and eggs, improves product quality, promotes antibody production, and enhances animal immunity.

Structure of Astaxanthin

Lifeasible can produce natural astaxanthin by fermentation and has a mature system and rich experience in isolation of astaxanthin-producing strains, selection and breeding of high-yielding strains, selection of astaxanthin fermentation process, and optimization of astaxanthin extraction technology.

Methods Strain Features
Astaxanthin production using algae Haematococcus pluvialis It is recognized as the best biological source of natural astaxanthin. We improve the high biomass by optimizing the culture medium, and culture method, and determining the optimal culture conditions. And based on the higher biomass, we improve the nutritional and environmental conditions to induce the cells to synthesize astaxanthin in large quantities.
Astaxanthin production using yeast fermentation Phaffia rhodozyma

This strain contains the highest amount of astaxanthin. We can produce astaxanthin by fermentation using a variety of sugars as a carbon source. High-density culture is possible due to rapid cell metabolism reproduction. The production cycle is short, natural, and pollution-free, and the cell wall is easily broken. Astaxanthin produced by this method is trans-structured and can be used directly as a feed additive after breaking the wall.

We obtain excellent strains with high astaxanthin production, high-temperature tolerance, high fermentation temperature, and less degradation through selection and breeding methods such as mutagenesis breeding, protoplast fusion, and genetic engineering breeding. By optimizing the fermentation conditions, the yield of astaxanthin can be maximized.

Astaxanthin extraction and analysis services

  • Extraction. Depending on the situation, we use mechanical, physical, chemical, and enzymatic methods to break the cell wall to release astaxanthin.
  • Detection. We offer thin layer chromatography (TLC), column chromatography, and high-performance liquid chromatography (HPLC) methods for purification and detection. We can perform the analysis on a C18 reversed column or a silica gel forward column. For the control of the fermentation process, we also measure the total pigment content in the cells by spectrophotometer.

Astaxanthin is a promising bioengineered product with antioxidant, anti-cancer, and immune-enhancing properties, and can be used as a feed additive. Lifeasible provides our customers with services such as selection and breeding of high-yielding strains and optimization of fermentation processes. We are still exploring more key technologies to solve the problems of low astaxanthin yield and high production cost. We are always open to cooperation with our customers in the field of feed additives in the production of astaxanthin by fermentation. Please feel free to contact us.

For research use only, not intended for any clinical use.
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